ALCHESIS™: Extraction-Free Molecular Transport and Lysis Media for NAAT Workflows

Transform your molecular diagnostics workflow. Eliminate cold-chain logistics, skip spin-column purification, and go direct to amplification from any clinical, veterinary or environmental specimen.

ALCHESIS™ excels in NAAT workflows and also supports NASBA and TMA. It works on any kind of sample, human, animal or environmental, in line with the One Health approach.

Indigenous Patented Technology

Supports the One Health programme: human, animal and environmental samples

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Patented · Dispatch within 3–5 working days.

Why modern labs and field diagnostics choose ALCHESIS™

• No purification needed: bypass spin-columns, silica beads and organic extractions, saving hours of hands-on time and processing cost.
• Direct-to-amplification: advanced inhibitor-scavenging polymers let you pipette raw supernatant lysate straight into your PCR master mix, or go direct to LAMP.
• Cold-chain free: ambient-stable for 7 to 30+ days at room temperature. Ship and store without ice packs, dry ice or refrigeration.
• Excels in NAAT workflows and also supports NASBA and TMA.
• Any sample, One Health: one formulation for human clinical samples, animal (veterinary) blood and tissues, environmental water and soil, and hard-bodied arthropod vectors.
• 95°C thermal lysis ready and patented, developed in New Delhi by Ruhvenile® Biomedical.

From raw sample to amplification in 3 steps

1. Collect and mix.
   Combine your specimen with ALCHESIS™ at 1:1 or a targeted volumetric ratio in a standard microcentrifuge tube.
2. Lyse and inactivate.
   Pathogens are inactivated and nucleic acids released. For tough cells, heat at 90–95°C for 10–15 minutes. Fragile cells and blood-borne pathogens lyse instantly at ambient temperature.
3. Amplify directly.
   Centrifuge briefly to pellet debris, then pipette a small aliquot of the clear supernatant into your LAMP or PCR assay.

Engineered for diverse diagnostic frontiers

Clinical diagnostics	Sputum, blood, serum, plasma, urine, CSF, pus, swabs (nasal, throat, rectal) and reproductive fluids.
Veterinary and livestock health	Whole blood, milk, lymph nodes, dung and tissue biopsies for vector-borne and infectious diseases (for example Trypanosoma).
Vector surveillance	Mosquitoes, ticks, fleas, lice and mites.
Environmental and industrial safety	Wastewater, surface swabs, soil and sediment.

Specifications

Room temperature stability	7 to 30+ days
Mixing ratio	1:1 or a targeted volumetric ratio, in a standard microcentrifuge tube
Tough cells	Thermal lysis at 90–95°C for 10–15 minutes
Fragile cells and blood-borne pathogens	Instant ambient lysis
Downstream use	NAAT workflows (LAMP and PCR), plus NASBA and TMA, directly from the supernatant
Customisation	Volumes, packs and formulations on request

Pack sizes

Fill volume	Tube
0.25 mL	0.5 mL tube
0.5 mL	0.9 mL tube
0.9 mL	2.0 mL tube
1.5 mL	5.0 mL tube
Bulk	Custom quantity

Questions buyers ask

Which amplification methods does ALCHESIS™ support?

ALCHESIS™ excels in NAAT workflows such as LAMP and PCR, and also supports NASBA and TMA.

Do I need to extract DNA or RNA before PCR or LAMP?

No. After lysis, centrifuge briefly to pellet heavy debris and pipette a small aliquot of the clear supernatant directly into your PCR or LAMP reaction.

How long can samples be stored in ALCHESIS™?

The formulation is ambient-stable for 7 to 30+ days at room temperature, so samples can ship without ice packs or dry ice.

Can ALCHESIS™ be customised?

Yes. Volumes, pack sizes and bulk quantities can be customised to your requirement. Tell us your sample type and assay and we will propose a format.

Ready to upgrade your laboratory efficiency?

Discover how ALCHESIS™ can scale your throughput and cut operational bottlenecks. A patented indigenous product developed by Ruhvenile® Biomedical, New Delhi, India.

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